PDB Information

PDB4L6Q
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Linking phenotype to kinase: identification of a novel benzoxaborole hinge-binding motif for kinase inhibition and development of high-potency rho kinase inhibitors.
Akama, T., Dong, C., Virtucio, C., Sullivan, D., Zhou, Y., Zhang, Y.K., Rock, F., Freund, Y., Liu, L., Bu, W., Wu, A., Fan, X.Q., Jarnagin, K.
J.Pharmacol.Exp.Ther.
HeaderTransferase/Transferase Inhibitor
Released2013-06-12
Resolution2.790
CATH Insert Date06 Oct, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
B 07 Oct, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4l6qA01 10 Oct, 2013 3.30.200.20 Assigned
4l6qA02 10 Oct, 2013 1.10.510.10 Assigned
4l6qB01 10 Oct, 2013 3.30.200.20 Assigned
4l6qB02 10 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2