PDB Information

PDB4L2X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
Leung, C.Y., Park, J., De Schutter, J.W., Sebag, M., Berghuis, A.M., Tsantrizos, Y.S.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-06-04
Resolution2.550
CATH Insert Date05 Jan, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
F 06 Jan, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4l2xF00 09 Jan, 2014 1.10.600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P14324 FPPS_HUMAN Homo sapiens Farnesyl pyrophosphate synthase