PDB 4l0t

PDB Links
Overview

PDB Information

PDB	4L0T
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. Narwal, M., Koivunen, J., Haikarainen, T., Obaji, E., Legala, O.E., Venkannagari, H., Joensuu, P., Pihlajaniemi, T., Lehtio, L. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2013-06-01
Resolution	2.100
CATH Insert Date	03 Nov, 2013

PDB Images (9)

Image of CATH 4l0t

4l0t

PDB 4l0t

Image of CATH 4l0tA

4l0tA

PDB Chain 4l0tA

Image of CATH 4l0tB

4l0tB

PDB Chain 4l0tB

Image of CATH 4l0tC

4l0tC

PDB Chain 4l0tC

Image of CATH 4l0tD

4l0tD

PDB Chain 4l0tD

Image of CATH 4l0tA00

4l0tA00

CATH Domain 4l0tA00

Image of CATH 4l0tB00

4l0tB00

CATH Domain 4l0tB00

Image of CATH 4l0tC00

4l0tC00

CATH Domain 4l0tC00

Image of CATH 4l0tD00

4l0tD00

CATH Domain 4l0tD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	04 Nov, 2013	Chopped
B	04 Nov, 2013	Chopped
C	04 Nov, 2013	Chopped
D	04 Nov, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l0tA00	08 Nov, 2013	3.90.228.10	Assigned
4l0tB00	08 Nov, 2013	3.90.228.10	Assigned
4l0tC00	08 Nov, 2013	6.20.320.10	Assigned
4l0tD00	08 Nov, 2013	6.20.320.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2