PDB Information

PDB4KZQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity.
Narwal, M., Koivunen, J., Haikarainen, T., Obaji, E., Legala, O.E., Venkannagari, H., Joensuu, P., Pihlajaniemi, T., Lehtio, L.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-05-30
Resolution2.250
CATH Insert Date03 Nov, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 04 Nov, 2013 Chopped
B 04 Nov, 2013 Chopped
C 04 Nov, 2013 Chopped
D 04 Nov, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4kzqA00 08 Nov, 2013 3.90.228.10 Assigned
4kzqB00 08 Nov, 2013 3.90.228.10 Assigned
4kzqC00 08 Nov, 2013 6.20.320.10 Assigned
4kzqD00 06 Nov, 2013 6.20.320.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2