PDB 4ky4

PDB Information

PDB4KY4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceToxoplasma gondii
Primary Citation
Discovery of potent and selective inhibitors of Toxoplasma gondii thymidylate synthase for opportunistic infections.
Zaware, N., Sharma, H., Yang, J., Devambatla, R.K., Queener, S.F., Anderson, K.S., Gangjee, A.
ACS Med Chem Lett
HeaderOxidoreductase, Transferase
Released2013-05-28
Resolution2.790
CATH Insert Date24 Aug, 2014

PDB Images (33)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped
C 25 Aug, 2014 Chopped
D 25 Aug, 2014 Chopped
E 25 Aug, 2014 Chopped
F 25 Aug, 2014 Chopped
G 25 Aug, 2014 Chopped
H 25 Aug, 2014 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4ky4A01 28 Aug, 2014 3.40.430.10 Assigned
4ky4A02 28 Aug, 2014 Holding pen
4ky4A03 28 Aug, 2014 3.30.572.10 Assigned
4ky4B01 28 Aug, 2014 3.40.430.10 Assigned
4ky4B02 28 Aug, 2014 Holding pen
4ky4B03 28 Aug, 2014 3.30.572.10 Assigned
4ky4C01 27 Aug, 2014 3.40.430.10 Assigned
4ky4C02 27 Aug, 2014 Holding pen
4ky4C03 27 Aug, 2014 3.30.572.10 Assigned
4ky4D01 27 Aug, 2014 3.40.430.10 Assigned
4ky4D02 27 Aug, 2014 Holding pen
4ky4D03 27 Aug, 2014 3.30.572.10 Assigned
4ky4E01 27 Aug, 2014 3.40.430.10 Assigned
4ky4E02 27 Aug, 2014 Holding pen
4ky4E03 27 Aug, 2014 3.30.572.10 Assigned
4ky4F01 27 Aug, 2014 3.40.430.10 Assigned
4ky4F02 27 Aug, 2014 Holding pen
4ky4F03 27 Aug, 2014 3.30.572.10 Assigned
4ky4G01 27 Aug, 2014 3.40.430.10 Assigned
4ky4G02 27 Aug, 2014 Holding pen
4ky4G03 27 Aug, 2014 3.30.572.10 Assigned
4ky4H01 28 Aug, 2014 3.40.430.10 Assigned
4ky4H02 28 Aug, 2014 Holding pen
4ky4H03 28 Aug, 2014 3.30.572.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase
Q07422 DRTS_TOXGO Toxoplasma gondii Bifunctional dihydrofolate reductase-thymidylate synthase