PDB Information

PDB4KAK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Elucidating features that drive the design of selective antifolates using crystal structures of human dihydrofolate reductase.
Lamb, K.M., G-Dayanandan, N., Wright, D.L., Anderson, A.C.
Biochemistry
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-04-22
Resolution1.800
CATH Insert Date13 Oct, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Oct, 2013 Chopped
B 14 Oct, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4kakA00 16 Oct, 2013 3.40.430.10 Assigned
4kakB00 17 Oct, 2013 3.40.430.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase
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