PDB Information

PDB4K77
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors.
Labadie, S., Barrett, K., Blair, W.S., Chang, C., Deshmukh, G., Eigenbrot, C., Gibbons, P., Johnson, A., Kenny, J.R., Kohli, P.B., Liimatta, M., Lupardus, P.J., Shia, S., Steffek, M., Ubhayakar, S., Abbema, A.V., Zak, M.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-04-16
Resolution2.400
CATH Insert Date06 Oct, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
B 07 Oct, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4k77A01 10 Oct, 2013 3.30.200.20 Assigned
4k77A02 10 Oct, 2013 1.10.510.10 Assigned
4k77B01 10 Oct, 2013 3.30.200.20 Assigned
4k77B02 10 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P23458 JAK1_HUMAN Homo sapiens Tyrosine-protein kinase JAK1
P23458 JAK1_HUMAN Homo sapiens Tyrosine-protein kinase JAK1