PDB 4jvg

PDB Information

PDB4JVG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization.
Lavoie, H., Thevakumaran, N., Gavory, G., Li, J.J., Padeganeh, A., Guiral, S., Duchaine, J., Mao, D.Y., Bouvier, M., Sicheri, F., Therrien, M.
Nat.Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2013-03-25
Resolution3.090
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4jvgA01 09 Aug, 2013 3.30.200.20 Assigned
4jvgA02 09 Aug, 2013 1.10.510.10 Assigned
4jvgB01 09 Aug, 2013 3.30.200.20 Assigned
4jvgB02 09 Aug, 2013 1.10.510.10 Assigned
4jvgC01 09 Aug, 2013 3.30.200.20 Assigned
4jvgC02 09 Aug, 2013 1.10.510.10 Assigned
4jvgD01 09 Aug, 2013 3.30.200.20 Assigned
4jvgD02 09 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf