PDB 4jv6

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Overview

PDB Information

PDB	4JV6
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Small molecule inhibition of the KRAS PDEd interaction impairs oncogenic KRAS signalling Zimmermann, G., Papke, B., Ismail, S., Vartak, N., Chandra, A., Hoffmann, M., Hahn, S.A., Triola, G., Wittinghofer, A., Bastiaens, P.I., Waldmann, H. Nature
Header	Protein Binding/Inhibitor
Released	2013-03-25
Resolution	1.870
CATH Insert Date	07 Jul, 2013

PDB Images (3)

Image of CATH 4jv6

4jv6

PDB 4jv6

Image of CATH 4jv6B

4jv6B

PDB Chain 4jv6B

Image of CATH 4jv6B00

4jv6B00

CATH Domain 4jv6B00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
B	08 Jul, 2013	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4jv6B00	09 Aug, 2013	2.70.50.40	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
O43924	PDE6D_HUMAN	Homo sapiens	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta