PDB Information

PDB4JU3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
Stammers, T.A., Coulombe, R., Duplessis, M., Fazal, G., Gagnon, A., Garneau, M., Goulet, S., Jakalian, A., Laplante, S., Rancourt, J., Thavonekham, B., Wernic, D., Kukolj, G., Beaulieu, P.L.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-03-24
Resolution2.000
CATH Insert Date01 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 02 Dec, 2013 Chopped
B 02 Dec, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ju3A01 04 Dec, 2013 Holding pen
4ju3A02 04 Dec, 2013 Holding pen
4ju3B01 04 Dec, 2013 Holding pen
4ju3B02 04 Dec, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
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