PDB Information

PDB4J54
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Extreme Multidrug Resistant HIV-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1'-Pyrrolidinone or P2-Tris-tetrahydrofuran.
Agniswamy, J., Shen, C.H., Wang, Y.F., Ghosh, A.K., Rao, K.V., Xu, C.X., Sayer, J.M., Louis, J.M., Weber, I.T.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-02-07
Resolution1.550
CATH Insert Date07 Jul, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4j54A00 09 Aug, 2013 2.40.70.10 Assigned
4j54B00 09 Aug, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein
P03367 POL_HV1BR Human immunodeficiency virus type 1 (BRU ISOLATE) Gag-Pol polyprotein