PDB Information

PDB4IXV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis of quaternary alpha-amino acid-based arginase inhibitors via the Ugi reaction.
Golebiowski, A., Whitehouse, D., Beckett, R.P., Van Zandt, M., Ji, M.K., Ryder, T.R., Jagdmann, E., Andreoli, M., Lee, Y., Sheeler, R., Conway, B., Olczak, J., Mazur, M., Czestkowski, W., Piotrowska, W., Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Podjarny, A., Schroeter, H.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-28
Resolution2.300
CATH Insert Date15 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4ixvA00 20 Dec, 2013 3.40.800.10 Assigned
4ixvB00 20 Dec, 2013 3.40.800.10 Assigned
4ixvC00 20 Dec, 2013 3.40.800.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P78540 ARGI2_HUMAN Homo sapiens Arginase-2, mitochondrial
P78540 ARGI2_HUMAN Homo sapiens Arginase-2, mitochondrial
P78540 ARGI2_HUMAN Homo sapiens Arginase-2, mitochondrial