PDB 4iqb

PDB Information

PDB4IQB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceCaenorhabditis elegans
Primary Citation
Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.
Jarmula, A., Wilk, P., Maj, P., Ludwiczak, J., Dowiercial, A., Banaszak, K., Rypniewski, W., Ciesla, J., Dabrowska, M., Fraczyk, T., Bronowska, A.K., Jakowiecki, J., Filipek, S., Rode, W.
J. Mol. Graph. Model.
HeaderTransferase
Released2013-01-11
Resolution1.130
CATH Insert Date02 Feb, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Feb, 2014 Chopped
B 03 Feb, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4iqbA00 07 Mar, 2014 3.30.572.10 Assigned
4iqbB00 07 Mar, 2014 3.30.572.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans Thymidylate synthase
Q9Y052 Q9Y052_CAEEL Caenorhabditis elegans Thymidylate synthase