PDB 4ijw

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Overview

PDB Information

PDB	4IJW
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD-1). Li, J., Kennedy, L.J., Wang, H., Li, J.J., Walker, S.J., Hong, Z., O'Connor, S.P., Nayeem, A., Camac, D.M., Morin, P.E., Sheriff, S., Wang, M., Harper, T., Golla, R., Seethala, R., Harrity, T., Ponticiello, R.P., Morgan, N.N., Taylor, J.R., Zebo, R., Gordon, D.A., Robl, J.A. ACS Med Chem Lett
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-12-23
Resolution	2.350
CATH Insert Date	29 Jun, 2014

PDB Images (9)

Image of CATH 4ijw

4ijw

PDB 4ijw

Image of CATH 4ijwA

4ijwA

PDB Chain 4ijwA

Image of CATH 4ijwB

4ijwB

PDB Chain 4ijwB

Image of CATH 4ijwD

4ijwD

PDB Chain 4ijwD

Image of CATH 4ijwE

4ijwE

PDB Chain 4ijwE

Image of CATH 4ijwA00

4ijwA00

CATH Domain 4ijwA00

Image of CATH 4ijwB01

4ijwB01

CATH Domain 4ijwB01

Image of CATH 4ijwD01

4ijwD01

CATH Domain 4ijwD01

Image of CATH 4ijwE00

4ijwE00

CATH Domain 4ijwE00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	30 Jun, 2014	Chopped
B	30 Jun, 2014	Chopped
D	30 Jun, 2014	Chopped
E	30 Jun, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ijwA00	03 Jul, 2014	3.40.50.720	Assigned
4ijwB01	03 Jul, 2014	3.40.50.720	Assigned
4ijwD01	03 Jul, 2014	3.40.50.720	Assigned
4ijwE00	03 Jul, 2014	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1