PDB 4iju

PDB Information

PDB4IJU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD-1).
Li, J., Kennedy, L.J., Wang, H., Li, J.J., Walker, S.J., Hong, Z., O'Connor, S.P., Nayeem, A., Camac, D.M., Morin, P.E., Sheriff, S., Wang, M., Harper, T., Golla, R., Seethala, R., Harrity, T., Ponticiello, R.P., Morgan, N.N., Taylor, J.R., Zebo, R., Gordon, D.A., Robl, J.A.
ACS Med Chem Lett
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-12-23
Resolution2.350
CATH Insert Date29 Jun, 2014

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 30 Jun, 2014 Chopped
B 30 Jun, 2014 Chopped
D 30 Jun, 2014 Chopped
E 30 Jun, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ijuA00 03 Jul, 2014 3.40.50.720 Assigned
4ijuB01 03 Jul, 2014 3.40.50.720 Assigned
4ijuD01 02 Jul, 2014 3.40.50.720 Assigned
4ijuE00 03 Jul, 2014 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1