PDB 4ifh

PDB Information

PDB4IFH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Deprez-Poulain, R., Hennuyer, N., Bosc, D., Liang, W.G., Enee, E., Marechal, X., Charton, J., Totobenazara, J., Berte, G., Jahklal, J., Verdelet, T., Dumont, J., Dassonneville, S., Woitrain, E., Gauriot, M., Paquet, C., Duplan, I., Hermant, P., Cantrelle, F.X., Sevin, E., Culot, M., Landry, V., Herledan, A., Piveteau, C., Lippens, G., Leroux, F., Tang, W.J., van Endert, P., Staels, B., Deprez, B.
Nat Commun
HeaderHydrolase/Hydrolase Inhibitor
Released2012-12-14
Resolution3.290
CATH Insert Date22 Dec, 2013

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ifhA01 26 Dec, 2013 3.30.830.10 Assigned
4ifhA02 26 Dec, 2013 3.30.830.10 Assigned
4ifhA03 26 Dec, 2013 3.30.830.10 Assigned
4ifhA04 26 Dec, 2013 3.30.830.10 Assigned
4ifhB01 26 Dec, 2013 3.30.830.10 Assigned
4ifhB02 26 Dec, 2013 3.30.830.10 Assigned
4ifhB03 26 Dec, 2013 3.30.830.10 Assigned
4ifhB04 26 Dec, 2013 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme