PDB Information

PDB4I8Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1
Primary Citation
P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety.
Yedidi, R.S., Maeda, K., Fyvie, W.S., Steffey, M., Davis, D.A., Palmer, I., Aoki, M., Kaufman, J.D., Stahl, S.J., Garimella, H., Das, D., Wingfield, P.T., Ghosh, A.K., Mitsuya, H.
Antimicrob.Agents Chemother.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-12-04
Resolution1.750
CATH Insert Date04 Aug, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped
B 05 Aug, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4i8zA00 14 Aug, 2013 2.40.70.10 Assigned
4i8zB00 14 Aug, 2013 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein
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