PDB Information

PDB4I6B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Selective and brain-permeable polo-like kinase-2 (Plk-2) inhibitors that reduce alpha-synuclein phosphorylation in rat brain.
Aubele, D.L., Hom, R.K., Adler, M., Galemmo, R.A., Bowers, S., Truong, A.P., Pan, H., Beroza, P., Neitz, R.J., Yao, N., Lin, M., Tonn, G., Zhang, H., Bova, M.P., Ren, Z., Tam, D., Ruslim, L., Baker, J., Diep, L., Fitzgerald, K., Hoffman, J., Motter, R., Fauss, D., Tanaka, P., Dappen, M., Jagodzinski, J., Chan, W., Konradi, A.W., Latimer, L., Zhu, Y.L., Sham, H.L., Anderson, J.P., Bergeron, M., Artis, D.R.
Chemmedchem
HeaderTransferase/Transferase Inhibitor
Released2012-11-29
Resolution1.800
CATH Insert Date24 Nov, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4i6bA01 27 Nov, 2013 3.30.200.20 Assigned
4i6bA02 27 Nov, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NYY3 PLK2_HUMAN Homo sapiens Serine/threonine-protein kinase PLK2