PDB Information

PDB4I0H
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors
Mondal, K., Regnstrom, K., Morishige, W., Barbour, R., Beroza, P., Yao, N., Bova, M.P.
To be Published
HeaderHydrolase/Hydrolase Inhibitor
Released2012-11-16
Resolution2.200
CATH Insert Date28 Mar, 2013

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4i0hA01 10 Apr, 2013 2.40.70.10 Assigned
4i0hA02 10 Apr, 2013 2.40.70.10 Assigned
4i0hB01 10 Apr, 2013 2.40.70.10 Assigned
4i0hB02 10 Apr, 2013 2.40.70.10 Assigned
4i0hC01 10 Apr, 2013 2.40.70.10 Assigned
4i0hC02 10 Apr, 2013 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1