PDB 4i06

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Overview

PDB Information

PDB	4I06
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury. Van Zandt, M.C., Whitehouse, D.L., Golebiowski, A., Ji, M.K., Zhang, M., Beckett, R.P., Jagdmann, G.E., Ryder, T.R., Sheeler, R., Andreoli, M., Conway, B., Mahboubi, K., D'Angelo, G., Mitschler, A., Cousido-Siah, A., Ruiz, F.X., Howard, E.I., Podjarny, A.D., Schroeter, H. J.Med.Chem.
Header	Hydrolase
Released	2012-11-16
Resolution	1.800
CATH Insert Date	28 Mar, 2013

PDB Images (7)

Image of CATH 4i06

4i06

PDB 4i06

Image of CATH 4i06A

4i06A

PDB Chain 4i06A

Image of CATH 4i06B

4i06B

PDB Chain 4i06B

Image of CATH 4i06C

4i06C

PDB Chain 4i06C

Image of CATH 4i06A00

4i06A00

CATH Domain 4i06A00

Image of CATH 4i06B00

4i06B00

CATH Domain 4i06B00

Image of CATH 4i06C00

4i06C00

CATH Domain 4i06C00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped
B	28 Mar, 2013	Chopped
C	28 Mar, 2013	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4i06A00	10 Apr, 2013	3.40.800.10	Assigned
4i06B00	10 Apr, 2013	3.40.800.10	Assigned
4i06C00	10 Apr, 2013	3.40.800.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P78540	ARGI2_HUMAN	Homo sapiens	Arginase-2, mitochondrial
P78540	ARGI2_HUMAN	Homo sapiens	Arginase-2, mitochondrial
P78540	ARGI2_HUMAN	Homo sapiens	Arginase-2, mitochondrial