PDB 4hyh

PDB Information

PDB4HYH
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-based design and optimization of 2-aminothiazole-4-carboxamide as a new class of CHK1 inhibitors.
Huang, X., Cheng, C.C., Fischmann, T.O., Duca, J.S., Richards, M., Tadikonda, P.K., Reddy, P.A., Zhao, L., Arshad Siddiqui, M., Parry, D., Davis, N., Seghezzi, W., Wiswell, D., Shipps, G.W.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-11-13
Resolution1.700
CATH Insert Date28 Mar, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hyhA01 10 Apr, 2013 3.30.200.20 Assigned
4hyhA02 10 Apr, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1