PDB 4hxw

PDB Information

PDB4HXW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEnterococcus faecalis
Primary Citation
Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
Tari, L.W., Trzoss, M., Bensen, D.C., Li, X., Chen, Z., Lam, T., Zhang, J., Creighton, C.J., Cunningham, M.L., Kwan, B., Stidham, M., Shaw, K.J., Lightstone, F.C., Wong, S.E., Nguyen, T.B., Nix, J., Finn, J.
Bioorg.Med.Chem.Lett.
HeaderIsomerase/Isomerase Inhibitor
Released2012-11-12
Resolution1.690
CATH Insert Date28 Mar, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4hxwA00 01 Jul, 2013 3.30.565.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q839Z1 GYRB_ENTFA Enterococcus faecalis V583 DNA gyrase subunit B
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