PDB 4hw4

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Overview

PDB Information

PDB	4HW4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent myeloid cell leukemia 1 (Mcl-1) inhibitors using fragment-based methods and structure-based design. Friberg, A., Vigil, D., Zhao, B., Daniels, R.N., Burke, J.P., Garcia-Barrantes, P.M., Camper, D., Chauder, B.A., Lee, T., Olejniczak, E.T., Fesik, S.W. J.Med.Chem.
Header	Apoptosis
Released	2012-11-07
Resolution	1.530
CATH Insert Date	20 Jan, 2013

PDB Images (7)

Image of CATH 4hw4

4hw4

PDB 4hw4

Image of CATH 4hw4A

4hw4A

PDB Chain 4hw4A

Image of CATH 4hw4B

4hw4B

PDB Chain 4hw4B

Image of CATH 4hw4C

4hw4C

PDB Chain 4hw4C

Image of CATH 4hw4D

4hw4D

PDB Chain 4hw4D

Image of CATH 4hw4A01

4hw4A01

CATH Domain 4hw4A01

Image of CATH 4hw4B01

4hw4B01

CATH Domain 4hw4B01

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	21 Jan, 2013	Chopped
B	21 Jan, 2013	Chopped
C	21 Jan, 2013	Rejected
D	21 Jan, 2013	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hw4A01	24 Jan, 2013	1.10.437.10	Assigned
4hw4B01	24 Jan, 2013	1.10.437.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1
Q07820	MCL1_HUMAN	Homo sapiens	Induced myeloid leukemia cell differentiation protein Mcl-1