PDB 4htz
PDB Information
PDB | 4HTZ |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | X-ray Crystal Structure of Phosphodiesterase 2 in Complex with a Highly Selective, Nanomolar Inhibitor Reveals a Binding-Induced Pocket Important for Selectivity.
J.Am.Chem.Soc.
|
Header | Hydrolase |
Released | 2012-11-02 |
Resolution | 2.000 |
CATH Insert Date | 15 Sep, 2013 |
PDB Images (9)
PDB Prints
PDB Chains (4)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 16 Sep, 2013 | Chopped |
B | 16 Sep, 2013 | Chopped |
C | 16 Sep, 2013 | Chopped |
D | 16 Sep, 2013 | Chopped |
CATH Domains (4)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4htzA00 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
4htzB00 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
4htzC01 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
4htzD01 | 18 Sep, 2013 | 1.10.1300.10 | Assigned |
UniProtKB Entries (4)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |
O00408 | PDE2A_HUMAN | Homo sapiens | cGMP-dependent 3',5'-cyclic phosphodiesterase |