PDB Information

PDB4HLC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus subsp. aureus
Primary Citation
Sulfonylpiperidines as novel, antibacterial inhibitors of Gram-positive thymidylate kinase (TMK).
Martinez-Botella, G., Loch, J.T., Green, O.M., Kawatkar, S.P., Olivier, N.B., Boriack-Sjodin, P.A., Keating, T.A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-10-16
Resolution1.550
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hlcA00 11 Nov, 2012 3.40.50.300 Assigned
4hlcB00 11 Nov, 2012 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q6GJI9 KTHY_STAAR Staphylococcus aureus subsp. aureus MRSA252 Thymidylate kinase
Q6GJI9 KTHY_STAAR Staphylococcus aureus subsp. aureus MRSA252 Thymidylate kinase