PDB 4heg

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Overview

PDB Information

PDB	4HEG
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Human immunodeficiency virus type 1
Primary Citation	Novel P2 tris-tetrahydrofuran group in antiviral compound 1 (GRL-0519) fills the S2 binding pocket of selected mutants of HIV-1 protease. Zhang, H., Wang, Y.F., Shen, C.H., Agniswamy, J., Rao, K.V., Xu, C.X., Ghosh, A.K., Harrison, R.W., Weber, I.T. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-10-03
Resolution	1.460
CATH Insert Date	01 Sep, 2013

PDB Images (5)

Image of CATH 4heg

4heg

PDB 4heg

Image of CATH 4hegA

4hegA

PDB Chain 4hegA

Image of CATH 4hegB

4hegB

PDB Chain 4hegB

Image of CATH 4hegA00

4hegA00

CATH Domain 4hegA00

Image of CATH 4hegB00

4hegB00

CATH Domain 4hegB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	02 Sep, 2013	Chopped
B	02 Sep, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hegA00	10 Sep, 2013	2.40.70.10	Assigned
4hegB00	10 Sep, 2013	2.40.70.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P03367	POL_HV1BR	Human immunodeficiency virus type 1 (BRU ISOLATE)	Gag-Pol polyprotein
P03367	POL_HV1BR	Human immunodeficiency virus type 1 (BRU ISOLATE)	Gag-Pol polyprotein