PDB 4h7c

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Overview

PDB Information

PDB	4H7C
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Synthesis and structure-activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3. Heinrich, D.M., Flanagan, J.U., Jamieson, S.M., Silva, S., Rigoreau, L.J., Trivier, E., Raynham, T., Turnbull, A.P., Denny, W.A. Eur.J.Med.Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-09-20
Resolution	1.970
CATH Insert Date	28 Mar, 2013

PDB Images (3)

Image of CATH 4h7c

4h7c

PDB 4h7c

Image of CATH 4h7cA

4h7cA

PDB Chain 4h7cA

Image of CATH 4h7cA00

4h7cA00

CATH Domain 4h7cA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4h7cA00	10 Apr, 2013	3.20.20.100	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3