PDB 4h58

PDB Information

PDB4H58
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and Optimization of a Novel Series of Potent Mutant B-Raf(V600E) Selective Kinase Inhibitors.
Vasbinder, M.M., Aquila, B., Augustin, M., Chen, H., Cheung, T., Cook, D., Drew, L., Fauber, B.P., Glossop, S., Grondine, M., Hennessy, E., Johannes, J., Lee, S., Lyne, P., Mortl, M., Omer, C., Palakurthi, S., Pontz, T., Read, J., Sha, L., Shen, M., Steinbacher, S., Wang, H., Wu, A., Ye, M.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-09-18
Resolution3.100
CATH Insert Date28 Mar, 2013

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4h58A01 10 Apr, 2013 3.30.200.20 Assigned
4h58A02 10 Apr, 2013 1.10.510.10 Assigned
4h58B01 10 Apr, 2013 3.30.200.20 Assigned
4h58B02 10 Apr, 2013 1.10.510.10 Assigned
4h58C01 10 Apr, 2013 3.30.200.20 Assigned
4h58C02 10 Apr, 2013 1.10.510.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf