PDB Information

PDB4GSF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme.
Charton, J., Gauriot, M., Totobenazara, J., Hennuyer, N., Dumont, J., Bosc, D., Marechal, X., Elbakali, J., Herledan, A., Wen, X., Ronco, C., Gras-Masse, H., Heninot, A., Pottiez, V., Landry, V., Staels, B., Liang, W.G., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-08-27
Resolution2.700
CATH Insert Date15 Sep, 2013

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Sep, 2013 Chopped
B 16 Sep, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4gsfA01 30 Oct, 2013 3.30.830.10 Assigned
4gsfA02 30 Oct, 2013 3.30.830.10 Assigned
4gsfA03 30 Oct, 2013 3.30.830.10 Assigned
4gsfA04 30 Oct, 2013 3.30.830.10 Assigned
4gsfB01 30 Oct, 2013 3.30.830.10 Assigned
4gsfB02 30 Oct, 2013 3.30.830.10 Assigned
4gsfB03 30 Oct, 2013 3.30.830.10 Assigned
4gsfB04 30 Oct, 2013 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
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