PDB 4glw

PDB Information

PDB4GLW
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStreptococcus pneumoniae
Primary Citation
Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity.
Surivet, J.P., Lange, R., Hubschwerlen, C., Keck, W., Specklin, J.L., Ritz, D., Bur, D., Locher, H., Seiler, P., Strasser, D.S., Prade, L., Kohl, C., Schmitt, C., Chapoux, G., Ilhan, E., Ekambaram, N., Athanasiou, A., Knezevic, A., Sabato, D., Chambovey, A., Gaertner, M., Enderlin, M., Boehme, M., Sippel, V., Wyss, P.
Bioorg.Med.Chem.Lett.
HeaderLigase/Ligase Inhibitor
Released2012-08-15
Resolution2.000
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4glwA01 15 Nov, 2013 3.30.470.30 Assigned
4glwB01 15 Nov, 2013 3.30.470.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
C1CKI0 DNLJ_STRZP Streptococcus pneumoniae P1031 DNA ligase
C1CKI0 DNLJ_STRZP Streptococcus pneumoniae P1031 DNA ligase