PDB 4gl9

PDB Information

PDB4GL9
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceMus musculus
Primary Citation
SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
Kershaw, N.J., Murphy, J.M., Liau, N.P., Varghese, L.N., Laktyushin, A., Whitlock, E.L., Lucet, I.S., Nicola, N.A., Babon, J.J.
Nat.Struct.Mol.Biol.
HeaderTransferase/Transferase Inhibitor
Released2012-08-14
Resolution3.900
CATH Insert Date28 Mar, 2013

PDB Images (25)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped
C 28 Mar, 2013 Chopped
D 28 Mar, 2013 Chopped
E 28 Mar, 2013 Chopped
F 28 Mar, 2013 Chopped
G 28 Mar, 2013 Chopped
H 28 Mar, 2013 Chopped
I 28 Mar, 2013 Rejected
J 28 Mar, 2013 Rejected
K 28 Mar, 2013 Rejected
L 28 Mar, 2013 Rejected

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4gl9A01 10 Apr, 2013 3.30.200.20 Assigned
4gl9A02 10 Apr, 2013 1.10.510.10 Assigned
4gl9B01 10 Apr, 2013 3.30.200.20 Assigned
4gl9B02 10 Apr, 2013 1.10.510.10 Assigned
4gl9C01 10 Apr, 2013 3.30.200.20 Assigned
4gl9C02 10 Apr, 2013 1.10.510.10 Assigned
4gl9D01 10 Apr, 2013 3.30.200.20 Assigned
4gl9D02 10 Apr, 2013 1.10.510.10 Assigned
4gl9E00 14 Jun, 2013 3.30.505.10 Assigned
4gl9F00 01 Jul, 2013 3.30.505.10 Assigned
4gl9G00 01 Jul, 2013 3.30.505.10 Assigned
4gl9H00 01 Jul, 2013 3.30.505.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q62120 JAK2_MOUSE Mus musculus Tyrosine-protein kinase JAK2
Q62120 JAK2_MOUSE Mus musculus Tyrosine-protein kinase JAK2
Q62120 JAK2_MOUSE Mus musculus Tyrosine-protein kinase JAK2
O35718 SOCS3_MOUSE Mus musculus Suppressor of cytokine signaling 3
Q00560 IL6RB_MOUSE Mus musculus Interleukin-6 receptor subunit beta
Q00560 IL6RB_MOUSE Mus musculus Interleukin-6 receptor subunit beta
Q62120 JAK2_MOUSE Mus musculus Tyrosine-protein kinase JAK2
Q00560 IL6RB_MOUSE Mus musculus Interleukin-6 receptor subunit beta
Q00560 IL6RB_MOUSE Mus musculus Interleukin-6 receptor subunit beta
O35718 SOCS3_MOUSE Mus musculus Suppressor of cytokine signaling 3
O35718 SOCS3_MOUSE Mus musculus Suppressor of cytokine signaling 3
O35718 SOCS3_MOUSE Mus musculus Suppressor of cytokine signaling 3