PDB 4gfo

PDB Information

PDB4GFO
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Lead identification of novel and selective TYK2 inhibitors.
Liang, J., Tsui, V., Van Abbema, A., Bao, L., Barrett, K., Beresini, M., Berezhkovskiy, L., Blair, W.S., Chang, C., Driscoll, J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Halladay, J., Johnson, A., Kohli, P.B., Lai, Y., Liimatta, M., Mantik, P., Menghrajani, K., Murray, J., Sambrone, A., Xiao, Y., Shia, S., Shin, Y., Smith, J., Sohn, S., Stanley, M., Ultsch, M., Zhang, B., Wu, L.C., Magnuson, S.
Eur.J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-08-03
Resolution2.300
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gfoA01 09 Aug, 2013 3.30.200.20 Assigned
4gfoA02 09 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2