PDB 4gfn

PDB Links
Overview

PDB Information

PDB	4GFN
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Enterococcus faecalis
Primary Citation	Pyrrolopyrimidine inhibitors of DNA gyrase B (GyrB) and topoisomerase IV (ParE). Part I: Structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity. Tari, L.W., Trzoss, M., Bensen, D.C., Li, X., Chen, Z., Lam, T., Zhang, J., Creighton, C.J., Cunningham, M.L., Kwan, B., Stidham, M., Shaw, K.J., Lightstone, F.C., Wong, S.E., Nguyen, T.B., Nix, J., Finn, J. Bioorg.Med.Chem.Lett.
Header	Isomerase/Isomerase Inhibitor
Released	2012-08-03
Resolution	1.900
CATH Insert Date	28 Mar, 2013

PDB Images (3)

Image of CATH 4gfn

4gfn

PDB 4gfn

Image of CATH 4gfnA

4gfnA

PDB Chain 4gfnA

Image of CATH 4gfnA00

4gfnA00

CATH Domain 4gfnA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gfnA00	10 Apr, 2013	3.30.565.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q839Z1	GYRB_ENTFA	Enterococcus faecalis V583	DNA gyrase subunit B