PDB Information

PDB4GFD
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus subsp. aureus
Primary Citation
In Vivo Validation of Thymidylate Kinase (TMK) with a Rationally Designed, Selective Antibacterial Compound.
Keating, T.A., Newman, J.V., Olivier, N.B., Otterson, L.G., Andrews, B., Boriack-Sjodin, P.A., Breen, J.N., Doig, P., Dumas, J., Gangl, E., Green, O.M., Guler, S.Y., Hentemann, M.F., Joseph-McCarthy, D., Kawatkar, S., Kutschke, A., Loch, J.T., McKenzie, A.R., Pradeepan, S., Prasad, S., Martinez-Botella, G.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2012-08-03
Resolution1.800
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gfdA00 10 Nov, 2012 3.40.50.300 Assigned
4gfdB00 10 Nov, 2012 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P65248 KTHY_STAAM Staphylococcus aureus subsp. aureus Mu50 Thymidylate kinase
P65248 KTHY_STAAM Staphylococcus aureus subsp. aureus Mu50 Thymidylate kinase