PDB Information

PDB4G11
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Preparation and optimization of new 4-(morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives as PI3K beta inhibitors
Certal, V., Halley, F., Virone-Oddos, A., Thompson, F., Filoche-Romme, B., El-Ahmad, Y., Carry, J.C., Delorme, C., Karlsson, A., Abecassis, P.Y., Vincent, L., Bonnevaux, H., Nicolas, J.P., Morales, R., Michot, N., Vade, I., Louboutin, A., Perron, S., Doerflinger, G., Tric, B., Monget, S., Lengauer, C., Schio, L.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-07-10
Resolution3.400
CATH Insert Date18 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 19 Nov, 2012 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4g11A01 02 Jan, 2013 3.10.20.90 Assigned
4g11A02 02 Jan, 2013 2.60.40.150 Assigned
4g11A03 02 Jan, 2013 1.25.40.70 Assigned
4g11A04 02 Jan, 2013 3.30.1010.10 Assigned
4g11A05 02 Jan, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform