PDB 4fm7
PDB Information
PDB | 4FM7 |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Spirocyclic sulfamides as beta-secretase 1 (BACE-1) inhibitors for the treatment of Alzheimer's disease: utilization of structure based drug design, WaterMap, and CNS penetration studies to identify centrally efficacious inhibitors.
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2012-06-15 |
Resolution | 1.560 |
CATH Insert Date | 04 Nov, 2012 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 05 Nov, 2012 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4fm7A01 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
4fm7A02 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |