PDB 4fcp

PDB Information

PDB4FCP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.
Davies, N.G., Browne, H., Davis, B., Drysdale, M.J., Foloppe, N., Geoffrey, S., Gibbons, B., Hart, T., Hubbard, R., Jensen, M.R., Mansell, H., Massey, A., Matassova, N., Moore, J.D., Murray, J., Pratt, R., Ray, S., Robertson, A., Roughley, S.D., Schoepfer, J., Scriven, K., Simmonite, H., Stokes, S., Surgenor, A., Webb, P., Wood, M., Wright, L., Brough, P.
Bioorg.Med.Chem.
HeaderChaperone
Released2012-05-25
Resolution2.000
CATH Insert Date04 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4fcpA00 31 Aug, 2013 3.30.565.10 Assigned
4fcpB00 31 Aug, 2013 3.30.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha
P07900 HS90A_HUMAN Homo sapiens Heat shock protein HSP 90-alpha