PDB 4fcd

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Overview

PDB Information

PDB	4FCD
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Novel triazines as potent and selective phosphodiesterase 10A inhibitors. Malamas, M.S., Stange, H., Schindler, R., Lankau, H.J., Grunwald, C., Langen, B., Egerland, U., Hage, T., Ni, Y., Erdei, J., Fan, K.Y., Parris, K., Marquis, K.L., Grauer, S., Brennan, J., Navarra, R., Graf, R., Harrison, B.L., Robichaud, A., Kronbach, T., Pangalos, M.N., Brandon, N.J., Hoefgen, N. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-05-24
Resolution	2.020
CATH Insert Date	04 Nov, 2012

PDB Images (5)

Image of CATH 4fcd

4fcd

PDB 4fcd

Image of CATH 4fcdA

4fcdA

PDB Chain 4fcdA

Image of CATH 4fcdB

4fcdB

PDB Chain 4fcdB

Image of CATH 4fcdA00

4fcdA00

CATH Domain 4fcdA00

Image of CATH 4fcdB00

4fcdB00

CATH Domain 4fcdB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fcdA00	08 Feb, 2013	1.10.1300.10	Assigned
4fcdB00	08 Feb, 2013	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A