PDB 4fa3

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Overview

PDB Information

PDB	4FA3
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids; a New Class of Highly Potent and Selective Inhibitors of the Type 5 17-beta-hydroxysteroid Dehydrogenase AKR1C3 Jamieson, S.M., Brooke, D.G., Heinrich, D., Atwell, G.J., Silva, S., Hamilton, E.J., Turnbull, A.P., Rigoreau, L.J., Trivier, E., Soudy, C., Samlal, S.S., Owen, P.J., Schroeder, E., Raynham, T., Flanagan, J.U., Denny, W.A. J.Med.Chem.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2012-05-21
Resolution	2.200
CATH Insert Date	04 Nov, 2012

PDB Images (3)

Image of CATH 4fa3

4fa3

PDB 4fa3

Image of CATH 4fa3A

4fa3A

PDB Chain 4fa3A

Image of CATH 4fa3A00

4fa3A00

CATH Domain 4fa3A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fa3A00	10 Nov, 2012	3.20.20.100	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P42330	AK1C3_HUMAN	Homo sapiens	Aldo-keto reductase family 1 member C3