PDB 4ewh

PDB Links
Overview

PDB Information

PDB	4EWH
Method	X-RAY DIFFRACTION
Host Organism
Gene Source	Homo sapiens
Primary Citation	Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors. Jiao, X., Kopecky, D.J., Liu, J., Liu, J., Jaen, J.C., Cardozo, M.G., Sharma, R., Walker, N., Wesche, H., Li, S., Farrelly, E., Xiao, S.H., Wang, Z., Kayser, F. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-04-27
Resolution	2.500
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4ewh

4ewh

PDB 4ewh

Image of CATH 4ewhA

4ewhA

PDB Chain 4ewhA

Image of CATH 4ewhB

4ewhB

PDB Chain 4ewhB

Image of CATH 4ewhA01

4ewhA01

CATH Domain 4ewhA01

Image of CATH 4ewhA02

4ewhA02

CATH Domain 4ewhA02

Image of CATH 4ewhB01

4ewhB01

CATH Domain 4ewhB01

Image of CATH 4ewhB02

4ewhB02

CATH Domain 4ewhB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ewhA01	14 Aug, 2013	3.30.200.20	Assigned
4ewhA02	14 Aug, 2013	1.10.510.10	Assigned
4ewhB01	14 Aug, 2013	3.30.200.20	Assigned
4ewhB02	14 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q07912	ACK1_HUMAN	Homo sapiens	Activated CDC42 kinase 1
Q07912	ACK1_HUMAN	Homo sapiens	Activated CDC42 kinase 1