PDB 4eev

PDB Information

PDB4EEV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.
Yan, S.B., Peek, V.L., Ajamie, R., Buchanan, S.G., Graff, J.R., Heidler, S.A., Hui, Y.H., Huss, K.L., Konicek, B.W., Manro, J.R., Shih, C., Stewart, J.A., Stewart, T.R., Stout, S.L., Uhlik, M.T., Um, S.L., Wang, Y., Wu, W., Yan, L., Yang, W.J., Zhong, B., Walgren, R.A.
Invest New Drugs
HeaderTransferase/Transferase Inhibitor
Released2012-03-28
Resolution1.800
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4eevA01 08 Aug, 2013 3.30.200.20 Assigned
4eevA02 08 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor