PDB 4e6q

PDB Links
Overview

PDB Information

PDB	4E6Q
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors. Kulagowski, J.J., Blair, W., Bull, R.J., Chang, C., Deshmukh, G., Dyke, H.J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Harrison, T.K., Hewitt, P.R., Liimatta, M., Hurley, C.A., Johnson, A., Johnson, T., Kenny, J.R., Bir Kohli, P., Maxey, R.J., Mendonca, R., Mortara, K., Murray, J., Narukulla, R., Shia, S., Steffek, M., Ubhayakar, S., Ultsch, M., van Abbema, A., Ward, S.I., Waszkowycz, B., Zak, M. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-03-15
Resolution	1.950
CATH Insert Date	03 Jun, 2012

PDB Images (7)

Image of CATH 4e6q

4e6q

PDB 4e6q

Image of CATH 4e6qA

4e6qA

PDB Chain 4e6qA

Image of CATH 4e6qB

4e6qB

PDB Chain 4e6qB

Image of CATH 4e6qA01

4e6qA01

CATH Domain 4e6qA01

Image of CATH 4e6qA02

4e6qA02

CATH Domain 4e6qA02

Image of CATH 4e6qB01

4e6qB01

CATH Domain 4e6qB01

Image of CATH 4e6qB02

4e6qB02

CATH Domain 4e6qB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2012	Chopped
B	03 Jun, 2012	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4e6qA01	08 Jun, 2012	3.30.200.20	Assigned
4e6qA02	08 Jun, 2012	1.10.510.10	Assigned
4e6qB01	08 Jun, 2012	3.30.200.20	Assigned
4e6qB02	08 Jun, 2012	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2
O60674	JAK2_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK2