PDB 4dtk

PDB Information

PDB4DTK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases.
Dakin, L.A., Block, M.H., Chen, H., Code, E., Dowling, J.E., Feng, X., Ferguson, A.D., Green, I., Hird, A.W., Howard, T., Keeton, E.K., Lamb, M.L., Lyne, P.D., Pollard, H., Read, J., Wu, A.J., Zhang, T., Zheng, X.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-02-21
Resolution1.860
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4dtkA01 10 Nov, 2012 3.30.200.20 Assigned
4dtkA02 10 Nov, 2012 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1