PDB Information

PDB4DSO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Maurer, T., Garrenton, L.S., Oh, A., Pitts, K., Anderson, D.J., Skelton, N.J., Fauber, B.P., Pan, B., Malek, S., Stokoe, D., Ludlam, M.J., Bowman, K.K., Wu, J., Giannetti, A.M., Starovasnik, M.A., Mellman, I., Jackson, P.K., Rudolph, J., Wang, W., Fang, G.
Proc.Natl.Acad.Sci.USA
HeaderHydrolase
Released2012-02-19
Resolution1.850
CATH Insert Date27 May, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4dsoA00 08 Jun, 2012 3.40.50.300 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas