PDB Information

PDB4DEM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells.
Lin, Y.S., Park, J., De Schutter, J.W., Huang, X.F., Berghuis, A.M., Sebag, M., Tsantrizos, Y.S.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-01-20
Resolution1.850
CATH Insert Date27 May, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
F 28 May, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4demF00 08 Jun, 2012 1.10.600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P14324 FPPS_HUMAN Homo sapiens Farnesyl pyrophosphate synthase