PDB Information

PDB4DCE
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
Bryan, M.C., Whittington, D.A., Doherty, E.M., Falsey, J.R., Cheng, A.C., Emkey, R., Brake, R.L., Lewis, R.T.
J.Med.Chem.
HeaderTransferase/Inhibitor
Released2012-01-17
Resolution2.030
CATH Insert Date12 Feb, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 13 Feb, 2012 Chopped
B 13 Feb, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4dceA01 16 Feb, 2012 3.30.200.20 Assigned
4dceA02 16 Feb, 2012 1.10.510.10 Assigned
4dceB01 16 Feb, 2012 3.30.200.20 Assigned
4dceB02 16 Feb, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor