PDB Information

PDB4CQA
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourcePLASMODIUM FALCIPARUM
Primary Citation
In Vitro Resistance Selections for Plasmodium Falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-Binding Site and Altered Growth.
Ross, L.S., Javier Gamo, F., Lafuente-Monasterio, M.J.E., Singh, O.M.P., Rowland, P., Wiegand, R.C., Wirth, D.F.
J.Biol.Chem.
HeaderOxidoreductase
Released2014-02-12
Resolution2.820
CATH Insert Date04 May, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 May, 2014 Chopped
B 05 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4cqaA00 09 May, 2014 3.20.20.70 Assigned
4cqaB00 09 May, 2014 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial
Q08210 PYRD_PLAF7 Plasmodium falciparum 3D7 Dihydroorotate dehydrogenase (quinone), mitochondrial