PDB Information

PDB4CME
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA BRUCEI BRUCEI
Primary Citation
Structure-Based Design and Synthesis of Antiparasitic Pyrrolopyrimidines Targeting Pteridine Reductase 1.
Khalaf, A.I., Huggan, J.K., Suckling, C.J., Gibson, C.L., Stewart, K., Giordani, F., Barrett, M.P., Wong, P.E., Barrack, K.L., Hunter, W.N.
J.Med.Chem.
HeaderOxidoreductase
Released2014-01-16
Resolution1.850
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4cmeA00 10 Jul, 2015 3.40.50.720 Assigned
4cmeB00 10 Jul, 2015 3.40.50.720 Assigned
4cmeC00 10 Jul, 2015 3.40.50.720 Assigned
4cmeD00 10 Jul, 2015 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase
O76290 O76290_TRYBB Trypanosoma brucei brucei Pteridine reductase