PDB Information

PDB4CK8
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceTRYPANOSOMA CRUZI
Primary Citation
Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma Cruzi Sterol 14Alpha-Demethylase: Two Regions of the Enzyme Molecule Potentiate its Inhibition.
Friggeri, L., Hargrove, T.Y., Rachakonda, G., Williams, A.D., Wawrzak, Z., Di Santo, R., De Vita, D., Waterman, M.R., Tortorella, S., Villalta, F., Lepesheva, G.I.
J.Med.Chem.
HeaderOxidoreductase
Released2013-12-30
Resolution2.620
CATH Insert Date10 Aug, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Aug, 2014 Chopped
B 11 Aug, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ck8A00 19 Aug, 2014 1.10.630.10 Assigned
4ck8B00 20 Aug, 2014 1.10.630.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase
Q7Z1V1 CP51_TRYCC Trypanosoma cruzi strain CL Brener Sterol 14-alpha demethylase
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