PDB 4cfn

PDB Information

PDB4CFN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI B
Gene SourceHOMO SAPIENS
Primary Citation
8-Substituted O6-Cyclohexylmethylguanine Cdk2 Inhibitors; Using Structure-Based Inhibitor Design to Optimise an Alternative Binding Mode.
Carbain, B., Paterson, D.J., Anscombe, E., Campbell-Dexter, A., Cano, C., Echalier, A., Endicott, J., Golding, B.T., Haggerty, K., Hardcastle, I.R., Jewsbury, P.J., Newell, D.R., Noble, M., Roche, C., Wang, L., Griffin, R.J.
J.Med.Chem.
HeaderCell Cycle
Released2013-11-19
Resolution2.200
CATH Insert Date22 Dec, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Chopped
C 23 Dec, 2013 Chopped
D 23 Dec, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4cfnA01 26 Dec, 2013 3.30.200.20 Assigned
4cfnA02 26 Dec, 2013 1.10.510.10 Assigned
4cfnB01 26 Dec, 2013 1.10.472.10 Assigned
4cfnB02 26 Dec, 2013 1.10.472.10 Assigned
4cfnC01 26 Dec, 2013 3.30.200.20 Assigned
4cfnC02 26 Dec, 2013 1.10.510.10 Assigned
4cfnD01 26 Dec, 2013 1.10.472.10 Assigned
4cfnD02 26 Dec, 2013 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
CATH-Gene3D is a Global Biodata Core Resource Learn more...